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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS3 All Species: 22.73
Human Site: Y353 Identified Species: 45.45
UniProt: Q68E01 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68E01 NP_075391.3 1043 118070 Y353 L R C D L I R Y I C G V V H P
Chimpanzee Pan troglodytes XP_001143923 1108 125002 Y352 L R C D L I R Y I C G V V H P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852591 1046 117423 Y350 L R C D L I R Y I C G V V H P
Cat Felis silvestris
Mouse Mus musculus Q7TPD0 1041 117919 Y351 L R C D L I R Y I C G V V H P
Rat Rattus norvegicus XP_342289 1041 117877 Y351 L R C D L I R Y I C G V V H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235108 302 34498
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LXC9 1017 116384 Y329 L R C D L I R Y I C G V V H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7PLS8 1068 123932 F329 L R S D L I R F I I N V I H P
Honey Bee Apis mellifera XP_394651 1035 118020 F325 L R C D L I R F I V G V I H P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786914 388 44969
Poplar Tree Populus trichocarpa XP_002298478 995 112510 F317 L V V D I I R F I C C A H H P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_193195 508 59017
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 N.A. 93.9 N.A. 98.5 98.3 N.A. N.A. 25.5 N.A. 83.3 N.A. 39 46 N.A. 24.2
Protein Similarity: 100 94 N.A. 95 N.A. 99.3 99.2 N.A. N.A. 27.5 N.A. 91 N.A. 60 66.9 N.A. 29.3
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 N.A. 100 N.A. 66.6 80 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 N.A. 100 N.A. 80 93.3 N.A. 0
Percent
Protein Identity: 24.6 N.A. N.A. 20.7 N.A. N.A.
Protein Similarity: 43.6 N.A. N.A. 33.4 N.A. N.A.
P-Site Identity: 53.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 66.6 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 59 0 0 0 0 0 0 59 9 0 0 0 0 % C
% Asp: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 75 0 % H
% Ile: 0 0 0 0 9 75 0 0 75 9 0 0 17 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 67 0 0 0 0 75 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 9 9 0 0 0 0 0 0 9 0 67 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _